![]() ![]() Based on the finite element simulation models established by PZFlex software, several ultrasound transducers with different concave curvatures were designed and analyzed. ![]() In this article, a miniaturized transducer with a half-concave structure is proposed. In preclinical studies, developing miniaturized transducers to facilitate neuromodulation in freely moving small animals is critical for understanding the mechanism and exploring potential applications. It is widely considered to be one of the most promising techniques for probing brain function and treating brain diseases. Transcranial ultrasound stimulation (TUS) is a young neuromodulation technology, which uses ultrasound to achieve non-invasive stimulation or inhibition of deep intracranial brain regions, with the advantages of non-invasive, deep penetration, and high resolution. 2Guangdong Institute of Intelligence Science and Technology, Zhuhai, China.1School of Microeletronics, Xidian University, Xi’an, China.Chenxue Hou 1†, Yan Wu 1†, Chunlong Fei 1*, Zhihai Qiu 2*, Zhaoxi Li 1, Xinhao Sun 1, Chenxi Zheng 1 and Yintang Yang 1
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